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Abstract #15721 Published in IGR 2-3
Short-wavelength automated perimetry and standard perimetry in the detection of progressive optic disc cupping
Girkin CA; Emdadi A; Sample PA; Blumenthal EZ; Lee AC; Zangwill LM; Weinreb RNArchives of Ophthalmology 2000; 118: 1231-1236
OBJECTIVE: To compare progression in short-wavelength automated perimetry (SWAP) and white-on-white (standard) perimetry in eyes with progressive glaucomatous changes of the optic disc detected by serial stereophotographs. METHODS: Forty-seven glaucoma patients with at least two disc stereophotographs more than two years apart, along with standard perimetry and SWAP examinations within six months of each disc photo of the same eye, were included in the study. The mean follow-up time was 4.1 years (range, 2.0-8.9 years). Baseline and follow-up stereophotographs were then graded and compared for the presence of progression. Progression in standard perimetry and SWAP, using the Advanced Glaucoma Intervention Study scoring system and a clinical scoring system, was compared between eyes with progressive change on stereophotographs and those without. RESULTS: Twenty-two of 47 eyes showed progressive change by stereophotographs. There was a statistically significant difference in the mean change in Advanced Glaucoma Intervention Study scores for both standard perimetry (p < 0.004) and SWAP (p < 0.001) between the progressed and nonprogressed groups. The sensitivity, specificity, and area under the receiver operator characteristic curve were higher using SWAP than standard perimetry when evaluated by either algorithm. This was statistically significant only in the area under the receiver operator characteristic curve for the Advanced Glaucoma Intervention Study scoring system (p = 0.04). CONCLUSIONS: SWAP identified more patients than standard perimetry as having progressive glaucomatous changes of the optic disc. Compared with standard perimetry, SWAP may improve the detection of progressive glaucoma.
Dr. C.A. Girkin, Glaucoma Center, University of California-San Diego, 9500 Gilman Dr, La Jolla, CA 92093-0946, USA
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)