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Abstract #15727 Published in IGR 2-3
Central corneal thickness in normals, patients with ocular hypertension, low-tension glaucomas, and open-angle glaucomas: a clinical study
Velten IM; Bergua A; Horn FK; Junemann A; Korth MKlinische Monatsblätter für Augenheilkunde 2000; 217: 219-224
BACKGROUND: The relationship between Goldmann applanation to nometry and central corneal thickness (CCT) has been investigated in several studies over the past 30 years. It was the aim of the present study to evaluate CCT in normals, and in patients with ocular hypertension, low-tension, and open-angle glaucoma. PATIENTS AND METHODS: CCT was measured in 135 normal eyes, 137 with ocular hypertension, 65 with low-tension, and 94 with primary and secondary open-angle glaucoma, using the AL-11000-pachymeter (Tomey). The results were compared using the unpaired t- est. RESULTS: CCT was significantly higher in patients with ocular hypertension (586 ± 43 μm) than in the normal group (566 ± 37 μm, p < 0.0001), low-tension glaucoma (555 ± 46 μm, p < 0.0001), or open-angle glaucoma (558 ± 31 μm, p < 0.0001) patients. The latter three groups did not differ significantly. There was no significant correlation between CCT and age, the IOP actually measured, the highest IOP in the patient's history, or the spherical equivalent. CONCLUSIONS: Only patients with ocular hypertension showed a significant difference in CCT compared to normals. Thus, pachymetry should be conducted in these patients to avoid overestimation of the IOP by applanation tonometry. However, according to the results of this study, in most patients with low-tension and open-angle glaucoma, taken without other parameters (e.g., corneal or scleral rigidity) CCT plays a minor role in the detection of elevated IOP.LA: German
Dr. I.M. Velten, Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)
