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Abstract #15874 Published in IGR 2-3
Retrobulbar hemodynamics in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure
Kondo Y; Niwa Y; Yamamoto T; Sawada A; Harris A; Kitazawa YAmerican Journal of Ophthalmology 2000; 130: 454-460
PURPOSE: To investigate retrobulbar hemodynamics by means of color Doppler imaging in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure. METHODS: Forty-nine consecutive patients who met the enrollment criteria were enrolled in a prospective study. The authors measured intraocular pressure at two-hour intervals for 24 hours, and performed color Doppler imaging of the orbital arteries, 48-hour ambulatory blood pressure monitoring, and visual field testing. Color Doppler parameters were compared between subjects with higher ocular perfusion pressure in the eye that had a better mean deviation (concordant group) and worse mean deviation (discordant group). RESULTS: In the eyes with the better mean deviation, the end-diastolic velocity of the ophthalmic artery was significantly slower in the discordant group (p = 0.0145), while in the eyes with the worse mean deviation, the peak systolic and end-diastolic velocities of the ophthalmic artery were significantly slower, and the resistance index of the ophthalmic artery was significantly higher in the discordant group (p = 0.0395, p = 0.0088, and p = 0.0324, respectively). In the concordant group, the end-diastolic velocity of the central retinal artery was slower in eyes with a worse mean deviation. CONCLUSION: Retrobulbar hemodynamics are significantly altered in patients with normal-tension glaucoma who have better ocular perfusion pressure in the eye that has a worse mean deviation.
Dr. T. Yamamoto, Department of Ophthalmology, Figu University School of Medicine, 40 Tsukasa-machi, Gifu-shi 500-8705, Japan. mmc-gif@umin.ac.jp
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
