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Abstract #15877 Published in IGR 2-3
Mitomycin C primary trabeculectomy with releasable sutures in primary glaucoma
Ünlü K; Aksünger A; Söker S; Ertem MJapanese Journal of Ophthalmology 2000; 44: 524-529
PURPOSE: To evaluate the effects of mitomycin C (MMC) and a releasable suture technique on outcomes of primary trabeculectomy in primary glaucoma patients. METHODS: A prospective analysis of patients who underwent primary trabeculectomy with a MMC concentration of 0.2 mg.ml for two minutes. For closing the scleral flap, releasable sutures were used in 18 patients (17 eyes; group 1), or permanent sutures in 18 patients (20 eyes; group 2). Clinical outcome factors including postoperative intraocular pressure (IOP), visual acuity, and incidence of complications, were determined. RESULTS: The mean follow-up periods were 8.1 ± 1.3 months in group 1 and 8.3 ± 1.3 months in group 2. The postoperative reduction in IOP was highly significant (p < 0.0001) at all time intervals in both groups. In all measurements of IOP before the second week, mean IOP in group 2 was found to be significantly lower than the mean IOP in group 1 (p = 0.01). No statistically significant differences were found between the groups at later mean IOP measurements. At the last visit, the complete success rate was 88.8% in group 1 and 85.0% in group 2. No serious complications, such as hypotonous maculopathy, were observed in any patient. CONCLUSIONS: Primary trabeculectomy with MMC in eyes with primary glaucoma showed effective IOP pressure reduction. There were no serious complications. In the early postoperative period, IOP was controlled better in the releasable suture group.
Dr. K. Ünlü, Department of Ophthalmology, University of Diele School of Medicine, 21280 Diyarbakir, Turkey
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
