advertisement
Abstract #15938 Published in IGR 2-3
Discoloration and hypertrichosis in the eyelids following instillation of latanoprost
Yamada NJapanese Journal of Clinical Ophthalmology 2000; 54: 1437-1440
Eyelid disorders were detected in 257 of 317 glaucoma patients (81.1%) following topical treatment with latanoprost ophthalmic solution once a day. Discoloration of eyelids was found in 128 cases (40.4%) and hypertrichosis in 244 cases (77.0%). The duration of latanoprost instillation ranged from 49-238 days. The incidence of eyelid disorders was the same in males and females, and was independent of the previous use of unoprostone. The total dose of latanoprost per eye averaged 2.9 bottles containing 2.5 ml. Eyelid changes developed even after instillation of one bottle per eye only in numerous cases. The abnormal findings gradually disappeared following cessation of medication. The above observation was made when the patients were not advised to wipe the eyelid after instillation. Further observation is under way after advising the patients to wipe the eyelid area thoroughly directly after instillation.LA: Japanese
Dr. N. Yamada, Yamada Eye Clinic, 1-39 Kaji-machi, Yokote-shi 013-0031, Japan
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
