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In order to study visual function in the early stage of primary open-angle glaucoma (POAG), pattern electroretinograms (P-ERGs), pattern visual evoked cortical potentials (P-VECPs), and multifocal electroretinograms (mERGs) were recorded from 12 patients (24 eyes) with POAG in the early stage. All the patients had unilateral glaucomatous visual field defects (i.e., stage II according to Kozaki's classification). The amplitude of P 50 in P-ERG was statistically significantly different for patients with stage II compared to stage I POAG, whereas the other components (latencies of N 35, P 50, and N 95; amplitude of N 95) were not statistically significantly different. No findings indicative of visual field defect were noted in P-VECPs and there were no abnormal findings in the first-order or the second-order kernel response components of mERGs. The second-order kernel response component of mERG was less useful than the amplitude of P 50 in the P-ERG for identifying a significant difference in visual function in the early stage of POAG.LA: Japanese
Dr. M. Yoshii, Department of Ophthalmology, National Defense Medical College, 3-2 Namiki, Tokorozawa 359-8513, Japan
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)