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Abstract #15988 Published in IGR 2-3
Corneal thickness and intraocular pressure in cases with ocular hypertension and glaucoma
Wu L; Suzuki Y; Araie MChinese Journal of Ophthalmology 2000; 36: 438
OBJECTIVE: To investigate the relationship between central corneal thickness (CCT) and intraocular pressure (IOP) in patients with ocular hypertension (OH), normal tension glaucoma (NTG), primary open-angle glaucoma (POAG), and normal subjects, as well as the importance of CCT in the diagnosis of glaucoma. METHODS: CCT was measured in 79 cases with NTG, 61 with POAG, 73 with OH, and 50 normal subjects using an ultrasonic pachymeter. One randomly selected eye of one subject was used for inter-group comparison. The maximum IOP measured by Goldmann applanation tonometry without ocular hypotensive therapy during follow-up was corrected with CCT using Ehlers' method. RESULTS: The CCT of OH subjects (582 ± 32 μm) was significantly thickness than that of other groups (p < 0.001), while no difference was seen in CCT between normal, NTG and POAG groups, the thickness being 552 ± 36, 548 ± 33, and 550 ± 33 μm, respectively. In the normal subjects, CCT was positively correlated with IOP (r = 0.423, p = 0.004). CONCLUSIONS: There is a large variation in CCT of normal subjects, which is significantly positively correlated with IOP. CCT is significantly thicker in OH subjects, which should be considered an important variable during follow-up. No significant difference in CCT was seen between NTG, POAG and normal groups. It is suggested that CCT has little influence on the diagnosis of NTG and POAG.LA: Chinese
Dr. L. Wu, Eye Center of the Second Affiliated Hospital, University of Zhejiang, School of Medicine, Hangzhou 310009, China
Classification:
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)