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Abstract #16782 Published in IGR 9-1
Axial length and optic disc size in normal eyes
Oliveira C; Harizman N; Girkin CA; Xie A; Tello C; Liebmann JM; Ritch RBritish Journal of Ophthalmology 2007; 91: 37-39
AIM: To investigate the relationship between optic disc area and axial length in normal eyes of white and black people. METHODS: Consecutive eligible normal subjects were enrolled. Ocular biometry was obtained using A-scan ultrasonography, and reliable images of the optic disc were obtained using a confocal scanning laser ophthalmoscope. The relationship between optic disc area and axial length was assessed using univariate and multivariate models. RESULTS: 281 eyes of 281 subjects were enrolled. Black subjects (n = 157) had significantly larger discs (mean (SD) disc area, 2.12 (0.5) mm2 ) than white subjects (n = 124; 1.97 (0.6) mm2 ; t test, p = 0.02). Optic disc area increased with axial length (Pearson's correlation coefficient, r = 0.13, p < 0.035) for the entire study population. Multivariate regression models including race, disc area and axial length showed that a significant but weak linear relationship exists between axial length and disc area (partial correlation coefficient 0.14; p < 0.024), and with race and disc area (partial correlation coefficient 0.19; p < 0.017) when adjusted for the effects of other terms in the model. CONCLUSION: Increased disc area is associated with longer axial length measurements and African ancestry. This may have implications for pathophysiology and risk assessment of glaucoma.
Dr. C. Oliveira, New York University School of Medicine, 310 East 14th Street suite 304, New York, NY 10003, USA
Classification:
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
