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1 General aspects (0)   1.1 Epidemiology (9)   1.2 Population genetics (1)   1.3 Pathogenesis (4)   1.4 Quality of life (6)   1.5 Glaucomas as cause of blindness (3)   1.6 Prevention and screening (3) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (0)   2.2 Cornea (18)   2.3 Sclera (2)   2.4 Anterior chamber angle (4)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (11)     2.5.2 Schlemms canal (0)     2.5.3 Scleral outlet channels (0)   2.6 Aqueous humor dynamics (1)     2.6.1 Production (2)     2.6.2 Outflow (2)       2.6.2.1 Trabecular meshwork (1)       2.6.2.2 Uveoscleral (3)     2.6.3 Compostion (4)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (0)   2.9 Ciliary body (1)   2.10 Lens (0)   2.11 Vitreous body (0)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (2)   2.13 Retina and retinal nerve fibre layer (22)   2.14 Optic disc (22)   2.15 Optic nerve (1)   2.16 Chiasma and retrochiasmal central nervous system (6)   2.17 Stem cells (1)   2.20 Other (0) 3 Laboratory methods (0)   3.1 Microscopy (1)   3.2 Electron microscopy (0)   3.3 Immunohistochemistry (8)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (1)     3.4.2 Gene studies (18)   3.5 Molecular biology incl. 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(4)

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Abstract #16802 Published in IGR 9-1

The effect of artificial tear administration on visual field testing in patients with glaucoma and dry eye

Yenice O; Temel A; Orum O
Eye 2007; 21: 214-217

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AIM: To examine the effects of artificial tear administration on perimetry of primary open-angle glaucoma patients with dry eye. METHODS: A total of 40 patients with primary open-angle glaucoma experienced in automated perimetry with symptoms of dry eye were enrolled in this study. After their pretest visit, they were instructed to use artificial tear four times a day in both eyes for 1 week. After 1 week, patients had visual field testing. Test taking time, reliability parameters (false-positive and false-negative errors) visual field indices and number of depressed points at different probability levels (P < 5%, P < 2%, P < 1%, P < 0.5%) in both total and pattern deviation plots were compared using paired Ttest. RESULTS: We found significant improvement in reliability parameters (false-positive errors from 2.4 ± 2.1 to 2.1 ± 1.9, P = 0.02; and false-negative errors from 7.3 ± 6.4 to 4.8 ± 3.6, P=0.01) and visual field indices (MD increased from 5.97 ± 5.61 to 4.57 ± 4.53, P = 0.001; PSD from 4.67 ± 2.95 to 4.13 ± 2.77, P = 0.04 and SF decreased from 2.24 ± 1.23 to 1.83 ± 0.77, P = 0.04) in the second testing after artificial tear administration. Test time significantly increased from 11.66 ± 2.55 min to 14.26 ± 1.36, P = 0.001. The number of depressed points at probability levels P < 1% (P = 0.03) and P < 0.5% (P = 0.04) at total deviation plot and P < 2% (P = 0.02) and P < 0.5% (P = 0.009) in pattern deviation plot decreased significantly. CONCLUSION: Artificial tear administration in glaucomatous patients with dry eye seems to improve significantly reliability parameters and visual field indices.

Dr. O. Yenice, Department of Ophthalmology, Marmara University School of Medicine, Kosuyolu Istanbul, Turkey. yeniceozlem@yahoo.com

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Classification:

6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)

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