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Abstract #16895 Published in IGR 9-1
Correlation of capsular pseudoexfoliation material and iridocorneal angle pigment with the severity of pseudoexfoliation glaucoma
Shuba L; Nicolela MT; Rafuse PEJournal of Glaucoma 2007; 16: 94-97
PURPOSE: To evaluate the correlation between the amount of pseudoexfoliation (PXF) material on the anterior lens capsule, pigment in the iridocorneal angle, presenting intraocular pressure (IOP) and severity of glaucoma in patients with PXF glaucoma/syndrome. PATIENTS AND METHODS: Anterior lens capsule PXF material and iridocorneal pigment of 98 untreated patients with PXF syndrome/glaucoma were graded from photographs and correlated with untreated IOP and indices of glaucoma severity (cup to disc ratio, and visual field mean deviation, and pattern standard deviation). RESULTS: There was a positive statistically significant correlation between the iridocorneal angle pigmentation and IOP (P = 0.047, R2 = 0.2), but not the indices of glaucoma severity (P > 0.13). There was no significant correlation between the anterior lens capsule PXF material and IOP or the indices of glaucoma severity (P > 0.42). The grade of angle pigmentation, but not lens PXF, in eyes with IOP > 21 mmHg was significantly higher than in eyes with IOP ≤ 21 mmHg (P = 0.04). CONCLUSIONS: In patients with PXF syndrome/glaucoma, gonioscopically identified iridocorneal angle pigmentation correlates more strongly with presenting IOP than the amount of PXF material on the anterior lens capsule.
Dr. L. Shuba, Department of Ophthalmology, 2 West 1278 Tower Rd, Halifax, NS, Canada B3H 2Y9
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
