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Abstract #16910 Published in IGR 9-1
25-gauge vitrectomy to treat ocular complications of familial amyloid polyneuropathy
Miyahara T; Ohta K; Yamamoto Y; Ueno A; Murata TJournal of Glaucoma 2007; 16: 169-170
PURPOSE: Secondary glaucoma and vitreous opacity with amyloid fibrils are the 2 major ocular complications of familial amyloid polyneuropathy (FAP). We investigated the feasibility of 25-gauge vitrectomy in excising the opaque vitreous into eyes that had already undergone trabeculectomy. METHODS: For the purpose of vision recovery, 25-gauge vitrectomy was performed in 2 eyes with vitreous amyloidosis. Both eyes had undergone trabeculectomy to treat glaucoma secondary to FAP. The survival of the filtration bleb after 25-gauge vitrectomy was also evaluated. RESULTS: Vision improved dramatically on the next day after the 25-gauge vitrectomy that causes minimal damage to the eye. No apparent complications including failure of the filtration bleb have been observed throughout the follow-up period of 6 months. CONCLUSIONS: 25-gauge vitrectomy has a potential to become a therapy of choice to excise opaque vitreous with amyloid fibrils in FAP, especially in the glaucomatous eyes that have already undergone trabeculectomy.
Dr. T. Miyahara, Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan. mteru@hsp.md.shinshu-u.ac.jp
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
12.16 Vitrectomy (Part of: 12 Surgical treatment)
