advertisement
Abstract #16942 Published in IGR 9-1
The Salzburg-Moorfields Collaborative Glaucoma Study: first results of the prevalence and 5-year incidences in this prospective, population-based longitudinal study
Hitzl W; Stollinger M; Grabner G; Reitsamer HA; Hornykewycz KKlinische Monatsblätter für Augenheilkunde 2006; 223: 970-973
BACKGROUND: This prospective, population-based longitudinal study describes prevalences and 5-year incidences of individuals with normal findings, ocular hypertension (OHT) and primary open-angle glaucoma (POAG) admitted to the Salzburg-Moorfields Collaborative Glaucoma Study (SMCGS). PATIENTS AND METHODS: The SMCGS is embedded in a government-supported glaucoma blindness prevention programme in Salzburg (Austria) which is designed for a minimum of 10-years follow-up. Each subject receives a complete ophthalmological examination. In total, the findings of 853 subjects with complete data sets were analysed and evaluated. RESULTS: The prevalence of participants with normal findings was 75% (95% CI: 72-78%) at the initial examination, decreasing to 64% (95% CI: 60-67%) at the 5-year follow-up. The prevalence of OHT at the initial exam of 2.3% (95% CI: 1.4-3.6%) increased to 3.5% (95% CI: 2.4-5.0%) at the 5-year follow-up exam with an incidence of 1.2% (95% CI: 0.6-2.2%). Finally, the prevalence of POAG of 0.6% (95% CI: 0.2-1.4%) increased to 1.6% (0.9-2.7%) at the 5-year exam which corresponds to a 5-year incidence of POAG of 1.0% (0.5-2.0%). CONCLUSION: The prevalence of POAG increases statistically significantly when compared at the initial and 5-year follow up exam (p = 0,002). Our results confirm the positive relation between age and the prevalence of POAG (odds ratio = 0.89, 95% CI: 0.81-0.98%). The prevalence and 5-year incidence rates in this glaucoma prevention study are similar to those of other population-based studies. LA: German
Dr. W. Hitzl, Universitätsklinik fur Ophthalmologie und Optometrie, St. Johanns-Spital, Paracelsus Medizinische Privatuniversität Salzburg, Österreich. W.Hitzl@salk.at
Classification:
1.1 Epidemiology (Part of: 1 General aspects)
