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Glaucoma is a multifactorial disease resulting in optic nerve atrophy if not treated properly. Large clinical trials (Collaborative Initial Glaucoma Treatment Study, Early Manifest Glaucoma Trial, Collaborative Normal Tension Glaucoma Study, Ocular Hypertension Treatment Study, Advanced Glaucoma Intervention Study) have identified intraocular pressure as the main risk factor for disease progression. The aim of modern medical glaucoma therapy is to reach reliably the patient's individual target pressure, furthermore to avoid significant diurnal fluctuations. Current medications from βblockers, prostaglandin-analogues, α-agonists, parasympathomimetics (miotics), carboanhydrase-inhibitors, hyperosmotics, as well as medications improving ocular blood flow, are listed and discussed. LA: German
Dr. J.F. Jordan. Zentrum fur Augenheilkunde, Universität zu Köln, Kerpener Str. 62, 50931 Köln. jens.jordan@uk-koeln.de
11.1 General management, indication (Part of: 11 Medical treatment)