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Abstract #17039 Published in IGR 9-1
Uses and complications of mitomycin C in ophthalmology
Mearza AA; Aslanides IMExpert Opinion on Drug Safety 2007; 6: 27-32
Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis. Its use and application in ophthalmology has been increasing in recent years because of its modulatory effects on wound healing. Current applications include pterygium surgery, glaucoma surgery, corneal refractive surgery, cicatricial eye disease, conjunctival neoplasia and allergic eye disease. Although it has been used successfully in these conditions, it has also been associated with significant complications. This article reviews the current trends and uses of mitomycin C in the eye and its reported complications.
Dr. I.M. Aslanides, Emmetropia Mediterranean Eye Institute, Parodos Anapoleos 7, Heraklion, Crete GR 71201, Greece. iaslanides@emmetropia.gr
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
