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Abstract #17056 Published in IGR 9-1
Circadian rhythms and the organ of sight
Urban E; Misiuk-Hojlo M; Kasprzak-Smolarek P; Rusiecka-Ziolkowska JAdvances in Clinical and Experimental Medicine 2006; 15: 953-957
Organisms from bacteria to humans have daily circadian rhythms entrained with the 24-hour cycle of day and night that regulate many physiological systems. An eye has the main role in a circadian's rhythm regulation because it is the only one organ which can detect light. There are two separate neural webs in a retina: the first one takes part in regulation of the visual cycle and the second one is connected with circadian rhythm. The primary mammalian circadian clock resides in the suprachiasmatic nucleus, located in the hypothalamus above the optic chiasm. Circadian clocks synchronize physiological functions with the solar day-night cycle. The knowledge of the eye circadian rhythm, intraocular pressure and aquous humor flow regulation is essential for optimal management of glaucomatous patients not only to interpret the single ocular tension recordings, but also to use the available treatment rationally, both drugs and surgery. LA: Polish
Dr. P. Kasprzak-Smolarek, ul. Litewska 10/68, 51-354 Wroclaw, Poland. sebany@interna.pl
Classification:
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
