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Abstract #17068 Published in IGR 9-1
Indocyanine green and fluorescein angiography study of glaucomatous peripapillary atrophy
Wu L-L; Chen W; Chen Z-Q; Yin J-F; Zhou H; Liu J; Su Z-AChinese Journal of Ophthalmology 2006; 42: 967-971
OBJECTIVE: To investigate the incidence of glaucomatous peripapillary atrophy (PPA) and choroidal circulation of glaucomatous patients. METHODS: The subjects of glaucoma groups included 43 (43 eyes) glaucomatous patients including 16 (16 eyes) chronic angle-closure glaucoma (CACG) 27 (27 eyes) open-angle glaucoma. Control group included 33 (33 eyes) cases. Indocyanine green angiography and fundus fluorescein angiography were performed on glaucoma groups and control group with Heidelberg retinal angiography (HRA) to observe α zone and β zone of PPA. RESULTS: The frequency of β zone in CACG, open-angle glaucoma and control group was 31. 3%, 77.8% and 21.9%, respectively, with statistically significant difference between these groups (Χ2 = 19.915, P = 0.000). β zone showed ICG hypofluorescence in all eyes. There were no statistically significant difference in the frequency of α zone between glaucoma groups and control group. However, there were two different types of indocyanine green filling in α zone: normal or decreased choroid filling. Decreased choroid filling in α zone was observed in 53.8% of eyes with chronic angle-closure glaucoma,66.7% of open-angle glaucoma and 32.1% of in control, the difference was significant (Χ2 = 6.648, P = 0.036). CONCLUSIONS: The frequency of zone β with no choroidal filling in open-angle glaucoma group is the highest among these three groups. Zone α in glaucomatous eyes show decreased choroidal circulation, which may be the early sign for the extension of β zone. LA: Chinese
Dr. L.-L. Wu, Peking University Third Hospital, Peking University Eye Center, Beijing 100083, China. wllc@mail.hz.zj.cn
Classification:
2.12 Choroid, peripapillary choroid, peripapillary atrophy (Part of: 2 Anatomical structures in glaucoma)
6.10.2 Posterior segment (Part of: 6 Clinical examination methods > 6.10 Fluorescein (ICG) angiography)
