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Abstract #17089 Published in IGR 9-1
Results of mitomycin C trabeculectomy combined with phacoemulsification and intraocular lens implantation for patients with primary open-angle glaucoma or normal-tension glaucoma
Fukuchi T; Suda K; Tanaka Y; Ueda J; Yaoeda K; Tanaka T; Fukushima A; Togano T; Nakatsue T; Ogawa AFolia Ophthalmologica Japonica / Nihon Ganka Kiyo 2006; 57: 672-677
PURPOSE: To evaluate the results of mitomycin C (MMC) trabeculectomy combined with phacoemulsification and intraocular lens implantation (trabeculectomy triple) for patients with primary open-angle glaucoma (POAG) or normal-tension glaucoma (NTG). METHODS: Trabeculectomy triple was performed in 31 eyes of 25 patients. The results were evaluated by Kaplan-Meier life table analysis. Trabeculectomy triple was considered to have failed if postoperative intraocular pressure (IOP) was decreased by less than 30% from the preoperative level. In addition, factors that could affect the outcome of surgery (patient age, sex, refraction, and diagnosis) were analyzed using the Cox proportional-hazards regression model. RESULTS: The average ± 1 standard deviation for patient age was 74.3 ± 5.89 years. The average preoperative IOP was 15.9 ± 3.14mmHg, the average 1 year after surgery was 12.2 ± 3.00mmHg, and the average 2 years postoperatively was 12.0 ± 3.59mmHg. The probability of success (achievement of 30% or greater reduction in IOP) was 25.8% at 1 year. Higher patient age or a diagnosis of NTG was risk factors for less reduction in IOP. CONCLUSIONS: In this study, it was difficult using trabeculectomy triple to achieve more than 30% reduction in IOP. One possible reason was that many eyes had low IOP preoperatively. In cases of low preoperative IOP, trabeculectomy triple is less successful in lowering IOP. LA: Japanese
Dr. T. Fukuchi, Div. of Ophthalmol. and Visual Science, Graduate School of Medical and Dental Sciences, Niigata Univ., 1-757 Asahimachi-dori, Niigata 951-8510, Japan.
Classification:
12.14.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.14 Combined cataract extraction and glaucoma surgery)
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
