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Abstract #17120 Published in IGR 9-1
Specular microscopy of the corneal endothelial in hypertension patients
Di Y; Wang Q-Q; Wu H-L; Yan Q-CInternational Journal of Ophthalmology 2006; 6: 1336-1338
AIM: To quantitatively analyze the corneal endothelial cell morphology of primary hypertensions with non-contact corneal endothelial microscope and to compare the difference with that of normal control group. METHODS: A total of 70 eyes (56 patients) of primary hypertension and 114 eyes (108 normal people) were examined and divided into 3 groups according to their ages. All the people were exduded glaucoma diabetes, high myopia injury and operation. SPSS10.0 software was used to analyze their mean cell area, mean cell density, coefficient of variation and percentage of hexagonal cells, t-test was used on statistical analysis. RESULTS: The corneal endothelium of 50-59 years old patients of hypertension showed no significant differences in cell density and area, but demonstrated a significantly higher coefficient of variation (t = 3.26, P < 0.05), a decrease in percentage of hexagonal cells compared to those in the control group (t = 3.86, P < 0.05). No significant difference on cell density was found in people of 60-69 years old between hypertension group and control group, presenting a higher cell area (t = 2.14, P < 0.05), lower coefficient of variation (t = 4.08, P < 0.05) and percentage of hexagonal cells (t = 5.19, P < 0.05). The corneal endothelia of ≥ 70 years old patients of hypertension showed no significant differences in cell density or cell area, but demonstrated a significantly decrease in percentage of hexagonal cells. CONCLUSION: Compared with the normal control, the morphology of corneal endothelial cells in patients with hypertension presents changes significantly on decrease of percentage of hexagonal cells and increase coefficient of variation. LA: Chinese
Dr. Q.-C. Yan, Department of Ophthalmology, China Medical University, Shenyang 110005 Liaoning Province, China. cmu4h-yqc@126.com
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
9.2.1 Ocular hypertension (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)