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Abstract #17177 Published in IGR 9-1

Diurnal variation of intraocular pressure following trabeculectomy with adjunct use of mitomycin C

Fukuda T; Nakamoto K; Yasuda N; Furusawa C
Japanese Journal of Clinical Ophthalmology 2006; 60: 1961-1963


PURPOSE: To report the diurnal variation of intraocular pressure (IOP) following trabeculectomy with adjunct use of mitomycin C. CASES AND METHOD: This study was made on 31 eyes of 20 cases of primary open-angle glaucoma. The series comprised 12 males and 8 females. Their ages ranged from 29 to 78 years, average 53 years. No patient had received ocular hypotensive drugs after surgery. IOP was measured 8 times a day during hospitalization 61 to 3,194 days, average 1,251 days, after surgery. Goldmann applanation tonometer was used throughout. RESULTS: 24-hour IOP in the whole series averaged 9.3 ± 3.5 mmHg. IOP was 9.9 ± 3.9 mmHg at 10 a.m. and 8.8 ± 3.5 mmHg at 1 a.m. The difference was significant (p < 0.05). There was a significant correlation between mean 24-hour IOP and range of IOP variation (R = 0.456). CONCLUSION: Physiological diurnal IOP variation is present in eyes after trabeculectomy with adjunct use of mitomycin C. Range of IOP variation is smaller in eyes with lower IOP. LA: Japanese

Dr. T. Fukuda, Department of Ophthalmology, Tokyo Metropolitan Police Hospital, 2-10-41 Fujimi, Tokyo 102-0071, Japan


Classification:

12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)



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