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Abstract #18360 Published in IGR 3-3
Preoperative latanoprost to prevent ocular hypertension after phacoemulsification and intraocular lens implantation
Lai JSM; Loo A; Tham CCY; Ho SY; Lam DSCJournal of Cataract and Refractive Surgery 2001; 27: 1792-1795
PURPOSE: To evaluate the efficacy of latanoprost given two hours preoperatively to prevent ocular hypertension in the early period after phacoemulsification and posterior chamber intraocular lens (PC IOL) implantation. METHODS: Sixty-four eyes of 64 patients with uncomplicated cataract having phacoemulsification with PC IOL implantation were included in this prospective randomized double-masked clinical trial. The eyes were randomly assigned to one of two groups: application of latanoprost 0.005% two hours before surgery or no latanoprost (control). Intraocular pressure (IOP) was measured three and 24 hours postoperatively. The anterior chamber was examined for the level of cells and flare using a slit-lamp biomicroscope. The level of significance was 5%. RESULTS: The decrease in mean IOP was not statistically significantly different between eyes receiving latanoprost two hours preoperatively and control eyes three (p = 0.843) and 24 (p = 0.721) hours postoperatively. CONCLUSIONS: A single application of latanoprost given two hours before phacoemulsification and PC IOL implantation did not produce a statistically significant IOP-lowering effect when compared with a control group in the first 24 hours after surgery.
Dr J.S.M. Lai, Department of Ophthalmology, United Christian Hospital, Kwun Tong, Kowloon, Hong Kong, China. jsmlai@netvigator.com
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)