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Abstract #18420 Published in IGR 3-3
A clinical analysis of 112 cases with glucocorticoid glaucoma
Yu M; Gao J; Ye TChung-Hua Min Kuo Hsiao Erh Ko i Hsueh Tsa Chih 2001; 37: 346-349
OBJECTIVE: To investigate the etiology, clinical characteristics, treatment, and prevention of glucocorticoid glaucoma (GIG). METHODS: Retrospectively, 112 cases (215 eyes) with GIG including 79 males and 33 females in the age range from six to 69 years were studied. RESULTS: One hundred and ten cases used glucocorticoid locally, two cases used it systemically, and the mean therapeutic time was 27.5 ± 23.18 months. Conjunctivitis of various causes was the main cause of using glucocorticoid, all 215 eyes had a defect of the visual field caused by hypertension, damage to the optic disc and retinal nerve fiber layers, as in primary open-angle glaucoma. The degree of injury was related to the therapeutic time. Intraocular pressure (IOP) was decreased after glucocorticoid use had been stopped, but it could not return to normal levels. There were 162 eyes (75.4%) with characteristic posterior subcapsular cataract and 76 cases with combined myopia. CONCLUSIONS: The most important cause leading to GIG is abuse of glucocorticoid. A history of using glucocorticoid and posterior subcapsular cataract are the main basis in the diagnosis and differential diagnosis of GIG. LA: Chinese
Dr M. Yu, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
