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Abstract #18429 Published in IGR 3-3
Morphometric characteristics of optic disc with disc hemorrhage in normal-tension glaucoma
Liou SY; Sugiyama K; Uchida H; Gu ZB; Yamamoto T; Tomita G; Kitazawa YAmerican Journal of Ophthalmology 2001; 132: 618-625
PURPOSE: To evaluate the morphometric characteristics of optic disc in eyes with and without disc hemorrhage in normal-tension glaucoma (NTG). METHODS: This was a prospective study conducted at Gifu University Hospital of 50 eyes of 50 patients with NTG (12 males, 38 females; age, 56.5 ± 14.1 years) who had developed new disc hemorrhage at the time of enrolment, and 58 eyes of 58 patients with NTG (20 males, 38 females; age, 56.7 ± 12.4 years) with no history of disc hemorrhage during the follow-up period of more than two years. Age and global indexes of the visual field were matched. Optic discs with and without hemorrhage were compared morphometrically using a scanning laser tomography. Global and sector analyses were made of the optic disc structural parameters. RESULTS: There was no significant difference in the global values of the disc parameters between the disc hemorrhage and nonhemorrhage groups. However, the inferotemporal values for the rim area, rim volume, mean retinal nerve fiber layer thickness, and retinal nerve fiber layer cross-section area in the disc hemorrhage group were significantly smaller than those in the nonhemorrhage group (p < 0.05). Moreover, in the disc hemorrhage group, the values for the rim area, rim volume, and retinal nerve fiber layer cross-section area in the inferotemporal sector with hemorrhage were significantly smaller than those in the same sector without hemorrhage (p < 0.05). CONCLUSIONS: Localized damage of the disc rim and retinal nerve fiber layer at the inferotemporal sector was prominent in eyes with disc hemorrhage.
Dr K. Sugiyama, Department of Ophthalmology, Gifu University School of Medicine, 40 Tsukawa-machi, Gifu-shi, 500-8705, Japan. ksugi-gif@umin.ac.jp
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)