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Abstract #18445 Published in IGR 3-3
Comparison of blood flow velocities of the extraocular vessels in patients with pseudoexfoliation or primary open-angle glaucoma
Yüksel N; Karabas VL; Demirci A; Arslan A; Altintas O; Caglar YOphthalmologica 2001; 215: 424-429
PURPOSE: To evaluate orbital blood flow velocities in patients with pseudoexfoliation glaucoma (PXG) or primary open-angle glaucoma (POAG). METHODS: Blood flow velocities in the ophthalmic, central retinal, and posterior ciliary arteries were evaluated by color Doppler imaging in 26 patients with PXG, 28 patients with POAG, and 30 age-matched normal controls. The results were compared. RESULTS: Compared to the controls, patients with PXG showed statistically significant decreased in the mean peak systolic and end-diastolic velocities, and increased mean resistive indices in all vessels except for the ophthalmic artery mean peak systolic velocity (p < 0.05). When compared to controls, patients with POAG showed statistically significant decreases in the mean end-diastolic velocities and increased mean resistive indices in all vessels measured (p < 0.05). No statistically significant differences were found in the mean blood flow parameters between POAG and PXG. CONCLUSIONS: Blood flow velocities of the retrobulbar vessels are decreased in patients with PXG. Reduced blood flow velocities may be secondary, as well as contributory, to exfoliative glaucomatous damage. Although there was no significant difference in the mean blood flow parameters between POAG and PXG, alterations in retrobulbar vessels might be associated with different pathogenic mechanisms of PXG.
Dr N. Yüksel, Department of Ophthalmology, Medical School of Kocaeli University, Kocaeli, Turkey
Classification:
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
