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Abstract #18958 Published in IGR 3-1
The combining measurement of the retinal nerve fiber layer thickness with elcetrophysiological test to detect primary open angle glaucoma
Mei W; Jian G; Yanfen Let al.Chinese Ophthalmic Research 2000; 18: 536-538
OBJECTIVE: To compare the sensitivity of measurement of the retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) and electrophysiological tests in the detection of primary open-angle glaucoma (POAG), and to analyze the relationship among them. METHODS: Twenty-six patients (50 eyes) with POAG at early, advanced, and late stages were tested with OCT and pattern electroretinogram (PERG), pattern visual evoked potentials (PVEP), oscillatory potentials (OPs). RESULTS: the abnormal rate of quantification of the RNFL thickness through OCT was 40.91% in early glaucoma, which was lower than that of PERG (78.95%) and PVEP (64.64%), but higher than that of OPs (28.57%). RNFL thickness in glaucoma was significantly related to the amplitudes of PERG and PVEP, and negatively to the latency of PVEP, not associated with overall amplitudes of OPs. CONCLUSIONS: It may be useful to apply both measurement of RNFL thickness with OCT and electrophysiological tests for detecting early glaucomatous damage. LA: Chinese
Dr W. Mei, Department of Ophthalmology, Sun Yat-sen Memorial Hospital, Sun Yatsen University of Medical Sciences, Guangzhou 510120, China
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
