advertisement
Abstract #19019 Published in IGR 3-1
Optic nerve head circulation after intraocular pressure reduction achieved by trabeculectomy
Tamaki Y; Araie M; Hasegawa T; Nagahara MOphthalmology 2001; 108: 627-632
OBJECTIVE: To study the effects of trabeculectomy and needling revision of poorly functioning blebs on the optic nerve head (ONH) circulation in patients with primary open-angle glaucoma (POAG). DESIGN: Prospective, nonrandomized, self-controlled trial. PARTICIPANTS: Nineteen POAG patients (age range, 52 ± 12 years; mean ± standard deviation) undergoing trabeculectomy and six POAG patients (age range, 62 ± 14 years) undergoing needling revision of the bleb. METHODS: Using the laser speckle method, the normalized blur (NB) value, a quantitative index of blood velocity, was determined every 0.125 seconds and averaged more than three cardiac pulses in the optic nerve head (NB(ONH)). MAIN OUTCOME MEASURES: The NB(ONH) and intraocular pressure (IOP) in both eyes, and blood pressure (BP) and pulse rate (PR) were measured before and two days and one, four, and eight weeks after trabeculectomy, and also before and ten and 40 minutes after needling procedures. RESULTS: Intraocular pressure in the operated eye was significantly decreased after trabeculectomy or needling procedures, and the ocular perfusion pressure was significantly increased by a maximum of 38%. The IOP in the unoperated eye, BP, and PR did not significantly change. NB(ONH) did not significantly change in either the operated or unoperated eye. CONCLUSIONS: Trabeculectomy and needling procedures induced little change in the ONH circulation.
Dr Y. Tamaki, Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
Classification:
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)