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A retrospective 12-year study on 35 patients with IOP values higher than 21 mmHg in repeated tonometric curves with no clinical glaucomatous-type signs, was carried out with the aim of discovering the incidence of eyes that evolved towards glaucomatous disease, in order to evaluate the role of preventive therapy and to observe how response to the ibopamine provocation test (which assesses outflow pathway compromission) was modified with time. The data obtained showed that, in 39.13% of the eyes, there was an evolution towards the disease. The ibopamine test was positive at time '0' (start of study) in 48.14% in the evolutive eyes and in 66.66% of the eyes which remained stable, while, at time '12' (end of study), almost all the eyes (92-95%) had become positive. The role of precociously initiated ocular hypotensive therapy concurring with the test positivity is put forward.
Dr J. Pecori Giraldi, Institute of Ophthalmology, La Sapienza University, Rome, Italy
9.1.3 Syndromes of Axenfeld, Rieger, Peters, aniridia (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)