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Abstract #19041 Published in IGR 3-1
Risk factors for open-angle glaucoma: a case-control study
Kaimbo DKW; Buntinx F; Missotten LJournal of Clinical Epidemiology 2001; 54: 166-171
The objective of this study was to identify possible risk factors associated with open-angle glaucoma (OAG). A case-control study included patients seen at an ophthalmological clinic. Cases were all consecutive new patients with either unilateral or bilateral OAG detected during the study period. Controls were a random sample of all other patients aged 30 years or more, seen in the same department in the same period. Data on demographic, anthropometric and diet habits, as well as medical characteristics, were collected from 144 patients by medical examination and interview. The study took place at the University Department of Ophthalmology and at a general private ophthalmology practice, both in the city of Kinshasa. Forty consecutive patients with OAG and 104 controls were chosen randomly between all consecutive non OAG patients. Odds ratio (OR) are presented for the relation between OAG and age, sex, ethnicity, family history of glaucoma, the length of stay in Kinshasa, body mass index, hypertension, diabetes mellitus, cigarette smoking, alcohol, diet habits. Adjusted odds ratio resulting from step-wise logistic regression was employed. Results indicate: family history of glaucoma (OR, 18; 95% CI, 5.80-59.00; p < 0.001), age (OR, 1.05; 95% CI, 1.01-1.09; p = 0.025), body mass index (OR, 1.09; 95% CI, 1.01-1.18; p = 0.05), hyperopia (OR, 2.9; 95% CI, 1.05-7.08; p = 0.03), the Mongo ethnic group (OR, 3.5; 95% CI, 1.11-12.20; p = 0.03), and the consumption of rice (OR, 4.6; 95% CI, 1.65-12.20; p = 0.004) conferred a significantly greater risk of OAG. This study seems confirm that the Mongo ethnic group is associated with an increased risk of OAG.
Dr F. Buntinx, Department of General Practice, Catholic University of Leuven, Kapucijnenvoer 33, B-3000 Leuven, Belgium
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)