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Abstract #19044 Published in IGR 3-1
Functional and structural measurements in a multifactorial glaucoma risk model
Polo V; Abecia E; Pablo LE; Pinilla I; Larrosa JM; Honrubia FMActa Ophthalmologica Scandinavica 2001; 79: 10-14
PURPOSE: To evaluate the relationship between a multifactorial probability risk model of developing glaucomatous visual field defects and the assessment of the retinal nerve fiber layer (RNFL) and short-wavelength automated perimetry (SWAP) in glaucoma suspects. METHODS: One hundred and fifty-seven eyes of 157 glaucoma suspects were included in the study. The risk of developing glaucomatous defects was assessed by applying a multifactorial model that included intraocular pressure, vertical cup-to-disc ratio, age and family history. Photographs of the RNFL and SWAP were performed. RESULTS: The SWAP was abnormal in 54 cases (34.3%); 21% of abnormal perimetries were obtained in the low-risk group, 37% in the moderate risk group and 56% in the high risk group. The nerve fiber layer evaluation in the different risk stages showed a pattern similar to the results obtained with SWAP. Multiple regression analyses, performed with the four variables included in the model with SWAP and RNFL evaluation, showed the relationship between the risk factors and the presence of glaucomatous damage - evaluated by RNFL and SWAP (p < 0001). CONCLUSIONS: The probability model showed a good correlation between the risk scale and the RNFL and SWAP assessment.
Dr V. Polo, Servicio de Oftalmologia, Hospital Miguel Servet, P. Isabel La Catolica 1 y 3, 50009 Zaragoza, Spain
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
