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Abstract #19053 Published in IGR 3-1
Acute glaucoma and paroxetine
Laplaud D; George A; Simon CAnnales de Psychiatrie 2000; 15: 67-70
Paroxetine is an antidepressant drug that has been introduced recently, is often prescribed, and belongs to inhibitors of serotonin reuptake. Its indications range from depressive episodes to either obsessive-compulsive disorders or prevention of panic attacks. It is well tolerated and has few anticholinergic side-effects. The authors report the case of a 63-year-old man, without any history of previous glaucoma, who presented angle-closure glaucoma that was due to paroxetine. The mechanisms at the origin of this type of glaucoma would not be anticholinergic side-effects. They would rather correspond to direct serotoninergic effects, and might even be due to the combination of both mechanisms. The authors therefore advocate the search for a history of either glaucoma or far-sightedness before prescription of paroxetine, and recommend to check the condition of the anterior chamber of the eye. LA: French
Dr C. Simon, Service d'Urgences Psychiatriques, CH Saint-Nazaire, BP 414, 44606 Saint-Nazaire, France
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
