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Abstract #19061 Published in IGR 3-1
Intraocular pressure decrease after phacoemulsification in patients with pseudoexfoliation syndrome
Merkur A; Damji KF; Mintsioulis G; Hodge WGJournal of Cataract and Refractive Surgery 2001; 27: 528-532
PURPOSE: to determine the intraocular pressure (IOP) response to phacoemulsification cataract extraction with posterior changer intraocular lens (PC IOL) implantation in patients with pseudoexfoliation syndrome (PEX). METHODS: A retrospective cohort study design assigned patients to one of three subgroups: PEX (n = 21); primary open-angle glaucoma (POAG) control (n = 23); and cataract control (n = 23). Inclusion criteria consisted of age older than 50 years, open angle by gonioscopy, and a cataract requiring phacoemulsification. The IOP response was determined at intervals up to 18 months. RESULTS: Postoperative IOP changes from baseline in the PEX group were -1.81, -4.52, and -2.31 mmHg at three, six, and 12 months, respectively. The changes in the POAG control group were -2.22, -2.32, and -1.88 mmHg, respectively, and in the cataract control group, -2.49, +0.45, and +0.28 mmHg, respectively. Patients in the PEX group had a reduction in IOP from baseline at all postoperative measurements. This reduction was significantly greater than in the POAG and cataract control groups at six months (p = 0.012 and p = 0.002, respectively) and 12 months (p = 0.001 and p = 0.050, respectively). CONCLUSIONS: Patients with PEX had a postoperative IOP reduction from baseline at all measurements, and a significantly greater reduction than patients in the POAG and cataract control groups at six and 12 months. Phacoemulsification cataract surgery with PC IOL implantation may be effective in managing patients with PEX who had elevated IOP and visually significant cataract, but no advanced optic nerve damage.
Dr K.F. Damji, University of Ottawa Eye Institute, 501 Smythe Road, Ottawa, Ontario KIH 8L6, Canada. Kdamji@ottawahospital.on.ca
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
