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Abstract #19062 Published in IGR 3-1
Intraocular pressure after phacoemulsification and intraocular lens implantation in nonglaucomatous eyes with and without exfoliation
Pohjalainen T; Vesti E; Uusitalo RJ; Laatikainen LTJournal of Cataract and Refractive Surgery 2001; 27: 426-431
To evaluate intraocular pressure (IOP) after phacoemulsification and intraocular lens (IOL) implantation in nonglaucomatous eyes with and without exfoliation. One hundred and ninety-six eyes that had phacoemulsification with IOL implantation were examined. Eyes with a history of intraocular disease or surgery that could affect IOP were excluded. The study comprised the remaining 160 eyes: 23 with exfoliation (EXF group) and 137 without exfoliation (non-EXF group). Follow-up data were available for 136 eyes. The same surgeon performed all surgeries. Patients were examined on the first postoperative day and after one week, four months, and 1.0-2.7 years. One day postoperatively, IOP rose in the EXF group from a mean preoperative level of 16.3 mmHg ± 2.7 (SD) to 21.0 ± 8.5 mmHg, a 28.4% increase (p = 0.0061). In the non-EXF group, mean IOP rose from 16.2 ± 3.4 mmHg to 20.5 ± 5.7 mmHg, a 29.9% increase (p = 0.001). In four eyes (17.4%) in the EXF group and eight eyes (5.8%) in the non-EXF group, IOP increased to 30 mmHg or higher at one day. After this, significant IOP decreases occurred in both the EXF and non-EXF group, respectively, as follows: 14.2 ± 3.0 mmHg (12.0% decrease from preoperative value; p = 0.001) and 15.0 ± 2.9 mmHg (5.9%; p = 0.001) one week postoperatively; 12.8 ± 2.7 mmHg (20.2%; p = 0.0002) and 13.8 ± 2.7 mmHg (13.2%; p = 0.001) after four months; and 12.3 ± 2.6 mmHg (23.2%; p = 0.0001) and 12.7 ± 2.7 mmHg (21.2%; p = 0.001) after 1.0-2.7 years. There was no significant difference between the two groups. After phacoemulsification with IOL implantation, IOP decreased significantly and remained lower than preoperatively in eyes with and without exfoliation. One day postoperatively, transient pressure peaks were more common in eyes with exfoliation. One eye without exfoliation developed glaucoma.
Dr T. Pohjalainen, Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
