advertisement
Abstract #19091 Published in IGR 3-1
The prevalence of cupping in end-stage arteritic and nonarteritic anterior ischemic optic neuropathy
Danesh-Meyer HV; Savino PJ; Sergott RCOphthalmology 2001; 108: 593-598
OBJECTIVE: To evaluate the prevalence of cupping in arteritic anterior ischemic optic neuropathy (AAION) and nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN: Retrospective, observational case series. PARTICIPANTS: Three hundred and one patients. METHODS: Review of clinical records and color fundus photographs. MAIN OUTCOME MEASURES: Photographic and clinical interpretation of optic nerve appearance. RESULTS: Ninety-two patients with AAION and 102 with NAION were included in the study. Disc photographs of 42 patients (48%) with AAION and 32 patients (31%) with NAION were available for reassessment. These were presented in a masked fashion along with a random sample of 27 disc pairs considered to be 'normal' and 27 disc pairs with 'established glaucoma' according to two examiners. Cupping was present in 92% of eyes with AAION secondary to giant cell arteritis and in 2% of eyes with NAION (kappa = 0.96; p < 0.001). CONCLUSIONS: The end-stage optic disc appearance in AAION secondary to giant cell arteritis is cupping, whereas segmental or diffuse pallor without cupping is the typical disc appearance after NAION.
Dr H.V. Danesh-Meyer, Discipline of Ophthalmology, University of Auckland, Auckland, New Zealand
Classification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
