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The purpose of this study was to report paradoxical reaction on the intraocular pressure after treatment with latanoprost in three cases of uveitic glaucoma. Serial clinical examinations of intraocular pressure by means of daily tonometric curves were performed in three patients with uveitic glaucoma before and after the beginning of latanoprost therapy. All measurements were performed by two doctors, but each patient's IOP was always measured by the same doctor. Adverse reactions, such as increased intraocular pressure and recurrence of inflammation, were noted to occur seven to 16 days after rechallenging with topical latanoprost therapy for glaucoma in patients with history of uveitic glaucoma. The conclusion indicates that clinicians should be alerted to these possible complications of topical latanoprost therapy in uveitic glaucoma.
Dr. S.C. Sacca, Department of Neurological, Section of Ophthalmology, University of Genoa, Viale Benedetto XV 1632, Genoa, Italy
11.4 Prostaglandins (Part of: 11 Medical treatment)