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Abstract #19190 Published in IGR 3-1
Outcome of trabeculectomy using mitomycin C of different concentrations: a short-term comparison of 0.2 and 0.4 mg/ml mitomycin C
Kawaji T; Miyagawa S-I; Negi AJapanese Journal of Clinical Ophthalmology 2000; 54: 1935-1938
The authors reviewed 110 eyes of glaucoma which underwent trabeculectomy with adjunct use of mitomycin C (MMC). The series comprised primary open-angle glaucoma 71 eyes, capsular glaucoma 24 eyes and angle-closure glaucoma 15 eyes. Low-concentration MMC of 0.2 mg/ml was used in 42 eyes and high-concentration MMC of 0.4 mg/ml in 68 eyes. The intraocular pressure (IOP) averaged 21.4 mmHg in the former group and 21.0 mmHg in the latter. The success rate, which was defined as IOP of 15 mmHg or less without medication six months after surgery, was 76.2% in the low-concentration group and 88.2% in the high-concentration group. There was no significant difference between the two groups. No significant differences were present between the two groups regarding postoperative complications including ocular hypotony and cataract. The findings show that similar hypotensive effect results six months after trabeculectomy whether using 0.2 mg/ml or 0.4 mg/ml MMC. LA: Japanese
Dr T. Kawaji, Department of Ophthalmology, Kumamoto University School of Medicine, 1-1-1 Honjou, Kumamoto-shi, 860-0811, Japan
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
