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Abstract #19288 Published in IGR 9-3

Pediatric keratoplasty in India: Indications and outcomes

Sharma N; Prakash G; Titiyal JS; Tandon R; Vajpayee RB
Cornea 2007; 26: 810-813


PURPOSE: To analyze the indications and outcomes of pediatric corneal transplantation surgery in a tertiary eye care center in the developing world. METHODS: In this longitudinal, retrospective study involving continuous cases, the records of 168 eyes of 154 children undergoing keratoplasty at a tertiary care center's specialized keratoplasty clinic during a 7-year period (1998-2004) were reviewed. The demography, etiology of opacification, visual acuity, and other findings were recorded. Intraoperative and postoperative details were reviewed. Major postoperative outcomes analyzed were visual acuity, graft survival, causes of graft failure, and follow-up duration. RESULTS: Infectious keratitis (43%) was the most common indication for keratoplasty, followed by congenital glaucoma (16.6%) and corneal trauma (11.2%). Overall 77% graft survival was seen at 36 months, and better graft outcome was associated with younger age and longer regular follow-up. Postoperatively, a best-corrected visual acuity (BCVA) > 20/200 could be achieved in only 30.1% of eyes at the last follow-up. Graft failure was seen in 18.4% of eyes, with graft infection being the most frequent cause (50%). Moreover, graft infection was the most common cause of graft failure in all age groups. CONCLUSIONS: In the developing world, infectious keratitis is the most common indication for pediatric keratoplasty and the most frequent cause of its failure.

Dr. R.B. Vajpayee, Corneal and Cataract Surgery, Centre for Eye Research Australia, University of Melbourne, 32, Gisborne Street, East Melbourne, Vic. 3002, Australia. rasikv@unimelb.edu.com


Classification:

2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
9.1.1 Congenital glaucoma, Buphthalmos (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)



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