advertisement
Abstract #19464 Published in IGR 9-3
Corneal thickness and visual field damage in glaucoma patients
Papadia M; Sofianos C; Iester M; Bricola G; Mete M; Traverso CEEye 2007; 21: 943-947
PURPOSE: To verify whether there was a significant correlation between central corneal thickness (CCT) and visual field damage in patients with primary open angle glaucoma (POAG). METHODS: A total of 99 eyes with POAG were consecutively recruited. Patients were classified as glaucomatous based on visual field and optic nerve head damage. All underwent applanation tonometry, Humphrey perimetry, and measurement of CCT with ultrasonic pachymetry. Based on CCT value, the sample was split at the mode in two groups (group 1<535 microm, n = 49; group 2 > or = 535 microm, n = 50). RESULTS: Entire cohort: mean CCT 554 microm ± 45.03; mean deviation (MD) -6.68 dB ± 7.32; pattern standard deviation (PSD) 5.33 ± 3.75; intraocular pressure (IOP) 17.91 ± 4.16 mmHg with treatment. Group 1: CCT was 504.8 microm ± 30.8; MD -9.01 dB ± 8.72; PSD 6.38 ± 3.99; IOP 18.02 mmHg ± 4.66. Group 2: mean CCT 574.6 microm ± 35.03; MD -4.39 dB ± 4.70; PSD 4.25 ± 3.19; IOP 17.79 mmHg ± 3.57. A significant difference was found between the two groups for both MD and PSD. Linear regression analysis showed a significant correlation between CCT and PSD (P < 0.001). CONCLUSIONS: Our data show that patients with a thinner cornea had a worse MD and PSD. As a thinner CCT causes an underestimation of the true IOP, there may be a delay in the diagnosis of POAG or an inadequate estimate of the clinical course despite apparently desirable IOP applanation readings.
Dr. M. Papadia, Centro di Ricerca Clinica e Laboratorio per il Glaucoma e la Cornea, Clinica Oculistica, DiNOG, University of Genova, Azienda Ospedaliera Universitaria San Martino, Genova, Italy
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
