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PURPOSE: To evaluate the effect of patient age on intraocular pressure (IOP) response after intravitreal injection of triamcinolone acetonide (IVTA). DESIGN: Interventional case series. METHODS: A total of 164 outpatients (164 eyes) aged 21 to 80 years (mean, 56.8 years), presenting with exudative age-related maculopathy (51) or macular edema of various etiologies (113), received IVTA (4 mg/0.1 ml). The primary outcome measure was IOP elevation > 21 mmHg. Patients were re-evaluated at one week, and one, three, and six months. RESULTS: The mean baseline IOP was 15.07 mmHg; the mean rise was 6.6 mmHg. IOP > 21 mmHg was observed in 42 (25.6%) patients. In the age group ≤ 45 years, IOP rise occurred in 45% (14/31) patients, compared with 21% (28/133) of older patients (P = .006). The groups were similar in baseline IOP, IOP rise, mean time-lag to maximum IOP, and response to treatment. CONCLUSIONS: IVTA caused more frequent IOP elevation in younger patients; other aspects of IOP response and its treatment were similar to older patients.
Dr. D. Shukla, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India. daksh66@gmail.com
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)