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(2)

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Abstract #19624 Published in IGR 9-3

Comparison of ultrasound biomicroscopic parameters after laser iridotomy in eyes with primary angle closure and primary angle closure glaucoma

Dada T; Mohan S; Sihota R; Gupta R; Gupta V; Pandey RM
Eye 2007; 21: 956-961

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PURPOSE: To study changes in anterior segment morphology after laser peripheral iridotomy (LPI) in primary angle closure (PAC) and primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM). METHODS: Ninety-three eyes of 93 patients underwent anterior segment evaluation including gonioscopy, disc evaluation with + 90D lens, applanation intraocular pressure, and standard achromatic perimetry. UBM was performed before and 2 weeks after Nd:YAG LPI to measure the trabecular-iris angle (TIA), the angle-opening distance (AOD 250/500), and the central anterior chamber depth (ACD). RESULTS: The superior TIA widened from a mean of 7.54 ± 3.15 to 15.66 ± 6.69 degrees (P = 0.0001), the inferior TIA increased from a mean of 9.0 ± 4.7 to 15.9 ± 6.8 degrees (P = 0.0001) after LPI in PAC. In PACG, the mean superior angle changed from 4.55 ± 2.5 to 6.12 ± 3.8 degrees (P = 0.4) and the inferior angle increased from 4.75 ± 2.0 to 7.9 ± 3.7 degrees (P = 0.1). The mean ACD increased from 2.19 ± 0.36 to 2.30 ± 0.36 mm in PAC group (P = 0.0003), with no significant change seen in the PACG group (1.79 ± 0.32 vs 1.82 ± 0.33 mm, P = 0.13). CONCLUSION: LPI leads to a widening of the anterior chamber angle and a deepening of the anterior chamber in eyes with PAC. It does not significantly change any anterior segment parameters in eyes with PACG.

Dr. T. Dada, Glaucoma Research Laboratory, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. tanujdada@hotmail.com

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Classification:

6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
12.2 Laser iridotomy (Part of: 12 Surgical treatment)
9.3.5 Primary angle closure (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)

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