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1 General aspects (0)   1.1 Epidemiology (11)   1.2 Population genetics (2)   1.3 Pathogenesis (4)   1.4 Quality of life (8)   1.5 Glaucomas as cause of blindness (7)   1.6 Prevention and screening (4) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (0)   2.2 Cornea (23)   2.3 Sclera (3)   2.4 Anterior chamber angle (5)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (10)     2.5.2 Schlemms canal (0)     2.5.3 Scleral outlet channels (0)   2.6 Aqueous humor dynamics (0)     2.6.1 Production (0)     2.6.2 Outflow (1)       2.6.2.1 Trabecular meshwork (1)       2.6.2.2 Uveoscleral (0)     2.6.3 Compostion (3)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (2)   2.9 Ciliary body (1)   2.10 Lens (0)   2.11 Vitreous body (0)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (2)   2.13 Retina and retinal nerve fibre layer (21)   2.14 Optic disc (14)   2.15 Optic nerve (2)   2.16 Chiasma and retrochiasmal central nervous system (1)   2.17 Stem cells (1)   2.20 Other (0) 3 Laboratory methods (0)   3.1 Microscopy (6)   3.2 Electron microscopy (0)   3.3 Immunohistochemistry (6)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (0)     3.4.2 Gene studies (12)   3.5 Molecular biology incl. 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Miscellaneous (9)

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Abstract #19670 Published in IGR 9-4

Glycosaminoglycans of the trabecular meshwork of the eye in primary juvenile glaucoma

Kuleshova ON; Zaidman AM; Korel' AV
Bulletin of Experimental Biology and Medicine 2007; 143: 381-384

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Significant changes in the qualitative and quantitative composition of glycosaminoglycans (decreased content of sulfated glycosaminoglycans and increased content of collagen-bound proteoglycanes) in the trabecular meshwork of the eye in primary juvenile glaucoma indicate fibrosis of the juxtacanalicular tissue, which was detected in pathomorphological examination of the operation material.

Dr. O.N. Kuleshova, S. N. Fedorov Center Ocular Microsurgery, Russian Ministry of Health, Novosibirsk, Russian Federation.

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Classification:

9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
3.7 Biochemistry (Part of: 3 Laboratory methods)
2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)

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