advertisement
Abstract #19725 Published in IGR 9-4
Assessment of glaucomatous visual field loss by local fluctuation of visual field
Koike T; Takahashi G; Urashima MTokyo Jikeikai Medical Journal 2007; 122: 73-78
PURPOSE: To compare the usefulness of local fluctuation and that of visual field parameters for assessing glaucomatous visual field loss. SUBJECTS AND METHODS: The subjects were 162 patients (323 eyes) who received perimetry two or more times at a mean age of 53 years. The mean observation period was three years and ten months. Two types of criteria were established for these subjects, and eyes with normal visual fields were included in the analysis. We investigated whether an abnormal visual field could be predicted by specific parameters of the Cox proportional-hazards model using an abnormal visual field in each criterion as an objective variable, and each measurement parameter obtained in a perimetry test as an explanatory variable. Measurement parameters included fixation loss, false positive, false negative, mean deviation, pattern standard deviation, short-term fluctuation, corrected pattern standard deviation, glaucoma hemifield test, local fluctuation (LF), and cluster. RESULTS: With both types of criteria, the presence of LF at any timepoint had a significant correlation with the appearance of an abnormal visual field: crude hazard ratio of 4.3 (95% confidence interval (CI):3.2-5.9) and adjusted hazard ratio of 4.9 (95% CI:3.4-7.0) in criterion 1; and crude hazard ratio of 3.0 (95% CI:2.4-3.8) and adjusted hazard ratio of 3.5 (95% CI:2.6-4.8) in the other criterion, according to the Cox proportional-hazards regression analysis. CONCLUSION: The presence of LF appears to be useful for predicting glaucomatous visual field loss in eyes with normal visual fields at the initial perimetry. LA: Japanese
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
