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Abstract #19734 Published in IGR 9-4

Massive extraocular extension and parotid lymph node metastasis of uveal melanoma

Harris MS; Harris GJ; Simons KB; Campbell BH
Ophthalmic Plastic and Reconstructive Surgery 2007; 23: 430-432


A 22-year-old man, diagnosed with unilateral glaucoma and treated with trabeculectomy six years earlier, presented with an epibulbar nodule of six months' duration. MRI displayed intra- and extraocular tumor, and gross invasion of the medial rectus muscle. Biopsy demonstrated uveal melanoma, and staging revealed enhancing ipsilateral parotid lymph nodes. Orbital exenteration and parotidectomy with selective neck dissection were performed. The tumor infiltrated superficial parotid nodes and extended into the parotid gland. The site of tumor origin is speculative, but a ring melanoma of the anterior chamber angle is suspected. Lymph node metastasis of uveal melanoma is rare; to our knowledge, this is the most advanced of the few reported cases.

Dr. G.J. Harris, Eye Institute, 925 North 87th Street, Milwaukee, WI 53226, USA. gjharris@mcw.edu


Classification:

9.4.3.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.3 Glaucomas associated with disorders of the iris and ciliary body)
9.4.8 Glaucomas associated with intraocular tumors (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)



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