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Abstract #19846 Published in IGR 9-4
Significance of retinal nerve fiber layer thickness measured by optical coherence tomography in the early diagnosis of glaucoma
Ji B-LInternational Journal of Ophthalmology 2007; 7: 1019-1021
AIM: To evaluate the significance of the retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography(OCT) in the early diagnosis of glaucoma. METHODS: The thickness of RNFL was measured by OCT in 41 patients with glaucoma (64 eyes) and 62 normal subjects (101 eyes). Comparisons were made with regard to the RNFL thickness of quadrants and in means between normal and glaucomatous group, and the thickness at different stages of glaucoma. The correlation between mean RNFL thickness and mean defect of visual field, and the sensitivity and specificity of mean RNFL thickness measured by OCT were calculated. RESULTS: There was significant difference of RNFL thickness in various quadrants and in means between normal and glaucomatous group (P < 0.05). With the course of glaucoma proceeding, RNFL thickness decreased. The mean RNFL thickness was highly positively correlated with mean defect of visual field (r = 0.722, P = 0.000). The sensitivity and specificity of mean RNFL thickness measured by OCT were 85.9% and 97.0% respectively. CONCLUSION: RNFL thickness measured by OCT provides a new method for early diagnosis of glaucoma. LA: Chinese
Dr. B.-L. Ji, Jinhua Eye Hospital, Jinhua 321000 Zhejiang Province, China. jbl954023@hotmail.com
Classification:
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
