advertisement
Abstract #20017 Published in IGR 9-4
Long-term therapeutic outcome of acute primary angle closure in Japanese
Sawada A; Aoyama A; Yamamoto T; Takatsuka NJapanese Journal of Ophthalmology 2007; 51: 353-359
PURPOSE: To investigate the long-term clinical course of acute primary angle closure (APAC) and acute primary angle-closure glaucoma (APACG) in Japanese patients. METHODS: We retrospectively reviewed our records of 66 consecutive APAC or APACG eyes observed between February 1992 and December 2003 (mean follow-up, 42.1 months). Immediately after the diagnosis, all patients had received similar medications to halt the acute attack. Subsequently, laser iridotomy or surgical peripheral iridectomy and/or laser iridoplasty were conducted. If intraocular pressure (IOP) control was poor under maximum tolerable ocular hypotensive agents, trabeculectomy with adjunctive mitomycin C (MMC) was undertaken. RESULTS: After laser therapy, the probability of success, defined as an IOP of < 21 mmHg with or without medications, was 81.2% ± 6.2%. In the ten eyes that were trabeculectomized, the probability of success based on the same criterion was 40.0% ± 29.7%. Multivariate analysis revealed that the degree of synechial angle closure (P = 0.029) and the preexistence of chronic glaucomatous optic neuropathy (P = 0.015) significantly influenced the need for subsequent filtering surgery. CONCLUSIONS: Without the intervention of filtering surgery, 84.6% of the eyes with APAC or APACG maintained IOP control with or without antiglaucoma medications. However, APAC and APACG eyes that eventually received trabeculectomy were predisposed to an uncontrollable IOP, even with the intraoperative application of MMC. The severity of APAC or APACG in Japanese may be affected by an underlying creeping angle closure.
Dr. A. Sawada, Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan. Sawadaa-gif@umin.ac.jp
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
13.2.1 IOP (Part of: 13 Therapeutic prognosis and outcome > 13.2 Outcome)
12.2 Laser iridotomy (Part of: 12 Surgical treatment)
12.7 Surgical iridectomy (Part of: 12 Surgical treatment)
