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OBJECTIVE: To assess whether there are variations in the intraocular pressure (IOP) between the morning and afternoon in healthy subjects. METHODS: This study was carried out in a Primary Care Health Center among usual patients of general practitioners. Two measurements of the intraocular pressure were assessed on the same day (between 8 and 9 a.m. and between 5 and 6 p.m.) using a Perkins applanation tonometer. The subjects (119 females and 101 males) had a mean age of 46.3 years, with ages ranging between 14 and 83 years. They were proportionally distributed among 4 age groups (14-24, 25-44, 45-64 and >65 years). RESULTS: The IOP mean values were: right eye, morning time and afternoon, 13.29 and 11.81 mmHg, respectively (p<0.001); left eye, morning time and afternoon, 13.48 and 12.04 mmHg (p<0.001). The IOP was significantly higher in males than in females, and showed a weak association with age. CONCLUSIONS: We found a diurnal variation of IOP of approximately 1.5 mmHg. The time of day when the IOP is measured needs to be considered as a variable in research in ocular hypertension and glaucoma. LA: Spanish
Dr. J.I. Jaen-Diaz, Centro de Salud Santa Maria de Benquerencia, C/. Guadarrama, s/n, 45007 Toledo, Spain. ijd02@hotmail.com
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)