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Abstract #20582 Published in IGR 10-1
Glaucoma is a neuronal disease
Caprioli JEye 2007; 21: S6-S10
In glaucoma, disease evolution may not be predicted only from intraocular pressure (IOP) in some patients, as successful IOP-lowering treatment does not always prevent progression. Some patients, such as those with normal-pressure glaucoma, may have more susceptible optic nerves than others. There are several reasons to characterise glaucoma as a neuronal disease, and there is some evidence that IOP is only one of a number of co-factors leading to glaucoma. This paper provides an overview of some of the mechanisms that may be operating at the level of the retinal ganglion cell.
Dr. J. Caprioli, Glaucoma Division, Jules Stein Eye Institute, University of California at Los Angeles (UCLA), Los Angeles, CA, USA
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
1.3 Pathogenesis (Part of: 1 General aspects)
