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Rezaie et al reported that the mutation of OPTN gene may be involved in the normal tension subtype of primary open angle glaucoma (POAG), and deduced that OPTN gene may play a protective role in the process of optic nerve lesion. The location, clone, structure, function and mutation were introduced in this review. LA: Chinese
Dr. X.-G. He, Department of Ophthalmology, Daping Hospital of the Third Military Medical University, Chongqing 400016, China. Xiangge_he@hotmail.com
3.4.2 Gene studies (Part of: 3 Laboratory methods > 3.4 Molecular genetics)