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1 General aspects (0)   1.1 Epidemiology (4)   1.2 Population genetics (0)   1.3 Pathogenesis (9)   1.4 Quality of life (7)   1.5 Glaucomas as cause of blindness (7)   1.6 Prevention and screening (3) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (3)   2.2 Cornea (23)   2.3 Sclera (1)   2.4 Anterior chamber angle (7)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (18)     2.5.2 Schlemms canal (0)     2.5.3 Scleral outlet channels (1)   2.6 Aqueous humor dynamics (0)     2.6.1 Production (0)     2.6.2 Outflow (0)       2.6.2.1 Trabecular meshwork (4)       2.6.2.2 Uveoscleral (1)     2.6.3 Compostion (8)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (3)   2.9 Ciliary body (2)   2.10 Lens (2)   2.11 Vitreous body (2)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (3)   2.13 Retina and retinal nerve fibre layer (43)   2.14 Optic disc (18)   2.15 Optic nerve (3)   2.16 Chiasma and retrochiasmal central nervous system (0)   2.17 Stem cells (0)   2.20 Other (1) 3 Laboratory methods (0)   3.1 Microscopy (1)   3.2 Electron microscopy (0)   3.3 Immunohistochemistry (7)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (0)     3.4.2 Gene studies (20)   3.5 Molecular biology incl. 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(12) 15 Miscellaneous (17)

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Abstract #20728 Published in IGR 10-1

The role of trimetazidine in the protection of the retina

Kaszuba-Bartkowiak K; Nowak MS; Jurowski P; Gos R
Archives of Medical Science 2007; 3: S65-S66

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Tissue ischaemia is an important factor in the development of several eye diseases. The commonly accepted idea regarding management of ischaemic effects is that a normal blood flow should be increased. Trimetazidine, an anti-ischaemic agent, can have a positive effect on retinal disorders with an ischaemic component. Trimetazidine seems to have an influence on selected visual parameters (improves visual acuity and contrast sensitivity) as an additional therapy in treatment of patients with primary open angle glaucoma and degenerative myopia. A positive effect on other retinal disorders with an ischaemic component, e.g. diabetic retinopathy, age-related macular degeneration (AMD) or inflammatory diseases, requires further investigations.

Dr. M.S. Nowak, Department of Ophthalmology and Visual Rehabilitation, Medical University of Lodz, 113 Zeromskiego Street, Lodz 90-549, Poland. michaelnovak@interia.pl

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Classification:

11.20 Other (Part of: 11 Medical treatment)

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