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PURPOSE: To evaluate the levels of serum α 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX. MATERIAL AND METHODS: Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry. RESULTS: The mean serum AAT concentration in PEX group was significantly higher than in the controls (p = 0.0001). CONCLUSION: Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
Dr. T. Cumurcu, Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
3.7 Biochemistry (Part of: 3 Laboratory methods)