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Abstract #20887 Published in IGR 10-2
Central corneal thickness in adult Chinese. Association with ocular and general parameters. The Beijing Eye Study
Zhang H; Xu L; Chen C; Jonas JBGraefe's Archive for Clinical and Experimental Ophthalmology 2008; 246: 587-592
BACKGROUND: To evaluate the distribution of central corneal thickness and its associations in the adult Chinese population. METHODS: The Beijing Eye Study 2006 is a population-based study including 3,251 (73.3%) subjects (aged 45+) out of 4,439 subjects who participated in the survey in 2001 and who returned for re-examination. Central corneal thickness (CCT) measurements were performed by slit lamp-based optical coherence tomography. RESULTS: Central corneal thickness measurement data were available for 3,100 (95.4%) subjects. Mean CCT was 556.2 ± 33.1 μm (median: 553 μm; range: 429-688 μm). In multiple regression analysis, CCT was significantly associated with optic disc area (P = 0.043), urban region (P < 0.001; odds ratio (OR): 4.77; 95% confidence interval (CI): 2.37, 7.17), male gender (P < 0.001; OR: 5.64; 95%CI: 2.57, 8.71), and intraocular pressure measurements (P < 0.001). It was not significantly associated with body weight (P = 0.54) and body height (P = 0.66), age (P = 0.17), and refractive error (P = 0.43). Intraocular pressure (measured by pneumotonometry) increased for each μm central corneal thickness increase by 0.03 mmHg. CONCLUSIONS: In the adult Chinese population, CCT was significantly associated optic disc area, urban region, and male gender. Intraocular pneumotonometric pressure measurements increased for each μm increase in central corneal thickness by 0.03 mmHg. CCT was not associated with age and refractive error.
Dr. H. Zhang, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
1.1 Epidemiology (Part of: 1 General aspects)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
