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Abstract #21108 Published in IGR 10-2

Optical coherence tomography of segmental optic hypoplasia

Unoki K
Neuro-Ophthalmology Japan 2007; 24: 414-425


Optical coherence tomography (OCT) images of segmental optic hypoplasia are described. Ophthalmoscopic and visual field features were determined in 4 patients (2 cases of superior segmental optic hypoplasia (SSOH), 1 case of inferior segmental optic hypoplasia and 1 case of temporal segmental optic hypoplasia). In both eyes of each patient, STRATUS-OCT (Humphrey Instrument, CA, USA) was used to obtain cross-sectional tomographies of the optic nerve head and the peripapillary retina. Circular scans around the optic disk in segmental optic hypoplasia revealed a marked decrease of the peripapillary RNFL thickness in the each quadrant but not in other quadrants. Vertical meridian scans through the optic nerve head showed that each of the segmental defects of the optic disk were associated with decreased RNPL thickness and an abnormal position of the retinal pigment epithelium near the region of the lamina cribrosa. The decrease of the peripapillary RNFL thickness was compared between 21 cases of SSOH and 11 cases of normal tension glaucoma with inferior visual field loss. The thin peripapillary RNFL thickness of SSOH was located in the superior-superionasal area, but in the glaucoma cases was located in the superior-superiortemporal area. Regarding clinical assessment of the segmental optic hypoplasia, OCT provides a new diagnostic tool, which helps to facilitate an understanding of the structural abnormalities of the optic disk as well as the selective defect of the retinal nerve fiber layer. LA: Japanese

Dr. K. Unoki Unoki Eye Clinic, Harara 1-7-15, Kagoshima-shi 890-0026, Japan


Classification:

10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)



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